144726-66-9Relevant academic research and scientific papers
SYNTHESIS AND PROPERTIES OF 1-ARYL-1,4-DIHYDRO-2,7-DIMETHYL-4-OXOPYRIDOPYRIMIDINE-6-CARBOXYLIC ACIDS AND THEIR DERIVATIVES
Deyanov, A. B.,Gavrilov, M. Yu.,Konshin, M. E.
, p. 449 - 453 (2007/10/02)
Acetylation of 2-arylamino-5-carbethoxy-6-methylnicotinonitriles gave N-acetyl-2-arylamino-5-carbethoxy-6-methylnicotinonitriles, which, under the influence of hydrogen chloride, are cyclized to 1-aryl-1,4-dihydro-6-carbethoxy-2,7-dimethyl-4-oxopyridopyrimidines.The latter can be converted to the corresponding carboxylic and hydroxamic acids, as well as to acetylation products 1-aryl-2-acetonyl-1,4-dihydro-6-carbethoxy-7-methyl-4-oxopyridopyrimidines.
