144734-46-3Relevant academic research and scientific papers
Chiral and achiral phosphine derivatives of alkylidyne tricobalt carbonyl clusters as catalyst precursors for (asymmetric) inter- and intramolecular Pauson-Khand reactions
Moberg, Viktor,Mottalib, M. Abdul,Sauer, Desiree,Poplavskaya, Yulia,Craig, Donald C.,Colbran, Stephen B.,Deeming, Antony J.,Nordlander, Ebbe
, p. 2442 - 2453 (2008)
Phosphine derivatives of alkylidyne tricobalt carbonyl clusters have been tested as catalysts/catalyst precursors in intermolecular and (asymmetric) intramolecular Pauson-Khand reactions. A number of new phosphine derivatives of the tricobalt alkylidyne clusters [Co3(μ3-CR)(CO) 9] (R = H, CO2Et) were prepared and characterised. The clusters [Co3(μ3-CR)(CO) 9-x(PR′3)x] (PR′3 = achiral or chiral monodentate phosphine, x = 1-3) and [Co3(μ 3-CR)(CO)7(P-P)] (P-P = chiral diphosphine; 1,1′- and 1,2-structural isomers) were assayed as catalysts for intermolecular and (asymmetric) intramolecular Pauson-Khand reactions. The phosphine-substituted tricobalt clusters proved to be viable catalysts/catalyst precursors that gave moderate to very good product yields (up to ～90%), but the enantiomeric excesses were too low for the clusters to be of practical use in the asymmetric reactions. The Royal Society of Chemistry.
