1447423-14-4

Basic information

• Product Name: 7-methyl-2-(4-fluorobenzyl)indole
• Synonyms: 7-methyl-2-(4-fluorobenzyl)indole
• CAS NO: 1447423-14-4
• Molecular Weight: 239.292
• Mol File: 1447423-14-4.mol

Chemical Properties

• CAS DataBase Reference: 7-methyl-2-(4-fluorobenzyl)indole(CAS DataBase Reference)
• NIST Chemistry Reference: 7-methyl-2-(4-fluorobenzyl)indole(1447423-14-4)
• EPA Substance Registry System: 7-methyl-2-(4-fluorobenzyl)indole(1447423-14-4)

Safety Data

• Hazardous Substances Data: 1447423-14-4(Hazardous Substances Data)

Upstream product

• 1418760-67-4 C₁₆H₁₄FN 
• 459-46-1 4-Fluorobenzyl bromide 
• 933-67-5 7-methyl-1H-indole 

Downstream Products

• 1447423-21-3 (-)-(S)-7-methyl-2-(4'-flurobenzyl)indoline 

Relevant articles and documents

Highly enantioselective hydrogenation of N-unprotected indoles using (S)-C10-BridgePHOS as the chiral ligand

(S)-C10-BridgePHOS was successfully applied to a highly efficient Pd-catalyzed enantioselective hydrogenation of substituted indoles. The methodology was suitable for the hydrogenation of indoles substituted at the 2-, 3- and 2,3-positions. Products were obtained in quantitative conversion and up to 98% ee. The role the 2-position substituent plays in the hydrogenation process has been proposed. The methodology could be used as an alternative method to synthesize extremely important chiral indolines from N-unprotected indoles.