144750-83-4 Usage
Description
3-IODO-1,5-DIHYDRO-4H-PYRAZOLO[3,4-D]PYRIMIDIN-4-ONE is a pyrazolo[3,4-d]pyrimidine derivative with the molecular formula C6H5IN4O. It features a pyrimidin-4-one core, an iodine atom at the 3-position, and a hydrogen atom at the 1-position. This chemical compound possesses potential pharmacological activities and is utilized in medicinal chemistry for the development of new drugs.
Uses
Used in Pharmaceutical Industry:
3-IODO-1,5-DIHYDRO-4H-PYRAZOLO[3,4-D]PYRIMIDIN-4-ONE is used as a precursor in the synthesis of new drugs due to its potential pharmacological activities. It is being studied for its possible biological activities, such as antitumor, antiviral, and antimicrobial properties, which could lead to the development of novel therapeutic agents.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 3-IODO-1,5-DIHYDRO-4H-PYRAZOLO[3,4-D]PYRIMIDIN-4-ONE serves as a valuable compound for investigating its potential therapeutic applications. The synthesis and study of this compound are crucial for understanding its biological activities and for advancing the creation of new pharmaceutical agents with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 144750-83-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,7,5 and 0 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 144750-83:
(8*1)+(7*4)+(6*4)+(5*7)+(4*5)+(3*0)+(2*8)+(1*3)=134
134 % 10 = 4
So 144750-83-4 is a valid CAS Registry Number.
InChI:InChI=1/C5H3IN4O/c6-3-2-4(10-9-3)7-1-8-5(2)11/h1H,(H2,7,8,9,10,11)
144750-83-4Relevant articles and documents
Synthesis of pyrazolo 3,4-d pyrimidine analogues of the potent agent N-4-2-2-amino-4 3H-oxo-7H-pyrrolo 2,3-d pyrimidin-5-yl ethylbenzoyl-L-glutamic acid (LY231514)
Taylor, Edward C.,Patel, Hemantkumar H.
, p. 8089 - 8100 (2007/10/02)
Several pyrazolo[3,4-d]pyrimidine analogues of the potent antitumor agent N-{4-[2-(2-amino-4(3 H)-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamic acid (LY231514, 5) have been prepared. A principal synthetic step proved to be a palladium-cata