1447729-40-9Relevant academic research and scientific papers
Synthesis of β-d-GalNAc(4,6-diS)(1-4)[α-l-Fuc(2,4-diS)(1-3)]- β-d-GlcA, a novel trisaccharide unit of chondroitin sulfate with a fucose branch
Tamura, Jun-Ichi,Tanaka, Haruna,Nakamura, Ayumi,Takeda, Naoko
, p. 3940 - 3943 (2013/07/25)
Novel glycosaminoglycans isolated from the body wall of sea cucumbers consist of chondroitin sulfates like polysaccharides. We have synthesized a representative repeating trisaccharide composed of a chondroitin backbone having a fucose (Fuc) branch at O-3 of glucuronic acid (GlcA), β-d-GalNAc(4,6- diS)(1-4)[α-l-Fuc(2,4-diS)(1-3)]-β-d-GlcA, in a stereocontrolled manner. Regiospecific sulfation at O-4,6 and O-2,4 of the N-acetylgalactosamine (GalNAc) and Fuc residues, respectively, was successfully achieved.
