1447827-91-9Relevant academic research and scientific papers
Synthesis of 6-Se-guanosine RNAs for structural study
Salon, Jozef,Gan, Jianhua,Abdur, Rob,Liu, Hehua,Huang, Zhen
, p. 3934 - 3937 (2013/09/02)
6-Se-guanosine phosphoramidite and RNAs have been synthesized by selenium substitution of the 6-oxygen atom, and it is revealed that the Se-derivatization is relatively stable and that bulge and wobble structures can better accommodate a large Se atom than a duplex. This Se-modification is useful in the structural study of RNAs and their protein complexes.
