1447829-02-8

Basic information

• Product Name: butyl (2R,3S)-3-(dodecylthio)-2-hydroxybutanoate
• CAS NO: 1447829-02-8
• Molecular Weight: 360.602
• Mol File: 1447829-02-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: butyl (2R,3S)-3-(dodecylthio)-2-hydroxybutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: butyl (2R,3S)-3-(dodecylthio)-2-hydroxybutanoate(1447829-02-8)
• EPA Substance Registry System: butyl (2R,3S)-3-(dodecylthio)-2-hydroxybutanoate(1447829-02-8)

Safety Data

• Hazardous Substances Data: 1447829-02-8(Hazardous Substances Data)

Upstream product

• 112-55-0 1-dodecylthiol 

Downstream Products

• 132513-51-0 n-butyl (S)-2-hydroxybutanoate 

Relevant articles and documents

Novel synthesis of butyl (S)-2-hydroxybutanoate, the key intermediate of PPARα agonist (R)-K-13675 from butyl (2 S,3 R)-epoxybutanoate and butyl (S)-2,3-epoxypropanoate

Novel synthetic methods for the production of butyl (S)-2-hydroxybutanoate starting from butyl (2S,3R)-epoxybutanoate or butyl (S)-2,3-epoxypropanoate were established. The former method utilized the regioselective thiolysis of the epoxybutanoate mediated by scandium triflate and subsequent reductive cleavage of the thioether to give butyl (S)-2-hydroxybutanoate with stereochemical retention in quantitative yield. The latter method utilized one-step conversion by a combination of methylmagnesium bromide and copper catalyst in high yield. Georg Thieme Verlag Stuttgart, New York.