144785-39-7

Basic information

• Product Name: (1S)-N,N-Dimethyl-1-<2-<(1S,3S)-3-hydroxy-3-isopropyl-1-oxo-1-thiapentyl>phenyl>ethylamine
• CAS NO: 144785-39-7
• Molecular Weight: 311.489
• Mol File: 144785-39-7.mol

Chemical Properties

• CAS DataBase Reference: (1S)-N,N-Dimethyl-1-<2-<(1S,3S)-3-hydroxy-3-isopropyl-1-oxo-1-thiapentyl>phenyl>ethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (1S)-N,N-Dimethyl-1-<2-<(1S,3S)-3-hydroxy-3-isopropyl-1-oxo-1-thiapentyl>phenyl>ethylamine(144785-39-7)
• EPA Substance Registry System: (1S)-N,N-Dimethyl-1-<2-<(1S,3S)-3-hydroxy-3-isopropyl-1-oxo-1-thiapentyl>phenyl>ethylamine(144785-39-7)

Safety Data

• Hazardous Substances Data: 144785-39-7(Hazardous Substances Data)

Upstream product

• 565-69-5 ethyl isopropyl ketone 
• 144785-35-3 (+)-N,N-Dimethyl-1-(2-methylsulfinylphenyl)ethylamine 

Relevant articles and documents

Asymmetric synthesis of (-)-(E)-5-hydroxy-5-isopropyl-3-hepten-2-one, a cembrane-derived compound from Greek tobacco

The lithiation of (+)-N,N-dimethyl-1-(2-methylsulfinylphenyl)-ethylamine (2) with butyllithium followed by reaction with unsymmetrical ketones gave the corresponding tert-alcohols with high diastereoselectivity. By following this procedure, (R)-(E)-5-hydroxy-5-isopropyl-3-hepten-2-ones (1), isolated from the extract of Greek tobacco, was synthesized and the absolute configuration on the asymmetric carbon determined.