144787-86-0Relevant academic research and scientific papers
Synthesis of anti-l,3-Diols through RuCl3/PPh3-Mediated Hydrogenation of β-Hydroxy Ketones: An alternative to organoboron reagents
Roche, Christophe,Labeeuw, Olivier,Haddad, Mansour,Ayad, Tahar,Genet, Jean-Pierre,Virginie, Ratovelomanana-Vidal,Phansavath, Phannarath
scheme or table, p. 3977 - 3986 (2010/02/27)
Hydrogenation of enantioenriched β-hydroxy ketones promoted by the catalyst generated in situ from commercially available and inexpensive RuCl 3 and PPh3 under hydrogen pressure allowed the efficient preparation of a variety of anti1
RuCl3/PPh3: An efficient combination for the preparation of chiral 1,3-anti-diols through catalytic hydrogenation
Labeeuw, Olivier,Roche, Christophe,Phansavath, Phannarath,Genet, Jean-Pierre
, p. 105 - 108 (2007/10/03)
(Chemical Equation Presented) An efficient economical alternative to the commonly used Evans' reagent for the diastereoselective reduction of β-hydroxy ketones is reported. Thus, ruthenium-mediated hydrogenation of enantioenriched β-hydroxy ketones using
Chiral Organosilicon Compounds in Asymmetric Synthesis of Chiral 1,3-Diols
Chan, T. H.,Nwe, K. T.
, p. 6107 - 6111 (2007/10/02)
Chiral 1,3-diols can be prepared in high enantiomeric purity (>99percent ee) from the reactions of the chiral silylcarbanion 2 with epoxides followed by oxidative cleavage of the carbon-silicon bond with hydrogen peroxide.The absolute configurations of so
