1447933-86-9Relevant academic research and scientific papers
Rapid two-step synthesis of benzimidazo[1′,2′:1,5]pyrrolo[2,3- c ]isoquinolines by a three-component coupling reaction
Narhe, Bharat D.,Tsai, Min-Huan,Sun, Chung-Ming
, p. 421 - 427 (2014/09/29)
A two-step, three-component coupling reaction on ionic liquid supported 2-cyanomethylbenzimidazoles, methyl 2-formylbenzoate, and isocyanides under microwave activation is explored. Knoevenagel condensation of 2-cyanomethylbenzimidazole with methyl-2-form
Regioselective piperidine-catalyzed tandem imination-isocyanate annulation to fused tricyclic triazines
Barve, Indrajeet J.,Chen, Chih-Hau,Kao, Chih-Hsien,Sun, Chung-Ming
supporting information, p. 244 - 249 (2014/06/09)
A novel tandem imination-isocyanate-mediated annulation was explored. Ionic liquid-immobilized 2-aminobenzimidazoles react sequentially with aldehydes and isocyanates to give highly functionalized benzimidazole-embedded triazines. The second-stage transformation revealed that the formation of triazinone functionality is entirely regioselective to allow rapid assembly of biologically interesting tricyclic skeletons. In conjunction with the application of microwave irradiation and IL support, this method provides an efficient route to access substituted benzoimidazotriazines.
