1447951-35-0Relevant academic research and scientific papers
Oxidative Addition to Palladium(0) Made Easy through Photoexcited-State Metal Catalysis: Experiment and Computation
Kancherla, Rajesh,Muralirajan, Krishnamoorthy,Maity, Bholanath,Zhu, Chen,Krach, Patricia E.,Cavallo, Luigi,Rueping, Magnus
, p. 3412 - 3416 (2019)
Visible-light induced, palladium catalyzed alkylations of α,β-unsaturated acids with unactivated alkyl bromides are described. A variety of primary, secondary, and tertiary alkyl bromides are activated by the photoexcited palladium metal catalyst to provide a series of olefins at room temperature under mild reaction conditions. Mechanistic investigations and density functional theory (DFT) studies suggest that a photoinduced inner-sphere mechanism is operative in which a barrierless, single-electron transfer oxidative addition of the alkyl halide to Pd0 is key for the efficient transformation.
