1447958-75-9Relevant academic research and scientific papers
TiCl4 mediated preparation of (E)-non-conjugated homoallylic alcohols with α-substituted allylsilanes
Albury, Aymara M.M.,Jennings, Michael P.
, p. 4487 - 4490 (2013/07/26)
The allylation of various aldehydes with α-substituted allylsilanes in the presence of TiCl4 has been investigated. It has been shown that these reagents readily allow for good yields and high to excellent diastereoselectivities (up to >20:1) for a series of aldehydes, thereby providing a means of preparing non-conjugated (E)-homoallylic alcohols in a single step.
