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4-Chloro-3,5-difluorobenzonitrile is a chemical compound with the molecular formula C7H2ClF2N. It is characterized by the presence of chlorine and fluorine atoms attached to a benzene ring, along with a nitrile group (CN) substituted onto the ring. 4-Chloro-3,5-difluorobenzonitrile is typically found as a white crystalline powder and is widely used as a reagent in the chemical industry, particularly for synthesizing complex molecules. Due to its reactive functional groups, it is essential to handle 4-Chloro-3,5-difluorobenzonitrile with caution to prevent harm to the skin and eyes or hazardous effects from ingestion or inhalation. Proper storage under controlled conditions is also crucial to maintain its stability and prevent any chemical alterations.

144797-57-9

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144797-57-9 Usage

Uses

Used in Chemical Synthesis:
4-Chloro-3,5-difluorobenzonitrile is used as a reagent in the chemical industry for the synthesis of various complex molecules. Its presence of reactive functional groups, such as chlorine, fluorine, and nitrile, makes it a valuable building block in the creation of a wide range of chemical compounds.
Used in Pharmaceutical Industry:
4-Chloro-3,5-difluorobenzonitrile is used as an intermediate in the synthesis of pharmaceutical compounds. Its unique structure and functional groups contribute to the development of new drugs with potential therapeutic applications.
Used in Material Science:
4-Chloro-3,5-difluorobenzonitrile is used as a precursor in the development of new materials with specific properties, such as high thermal stability or unique electronic characteristics. Its versatility in chemical reactions allows for the creation of materials with tailored properties for various applications.
Used in Research and Development:
4-Chloro-3,5-difluorobenzonitrile is used as a research compound in academic and industrial laboratories. Its reactivity and structural features make it an interesting subject for studies in organic chemistry, materials science, and related fields.

Check Digit Verification of cas no

The CAS Registry Mumber 144797-57-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,7,9 and 7 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 144797-57:
(8*1)+(7*4)+(6*4)+(5*7)+(4*9)+(3*7)+(2*5)+(1*7)=169
169 % 10 = 9
So 144797-57-9 is a valid CAS Registry Number.

144797-57-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Chloro-3,5-Difluorobenzonitrile

1.2 Other means of identification

Product number -
Other names 4-Chloro-3,5-difluorobenzonitrile

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:144797-57-9 SDS

144797-57-9Upstream product

144797-57-9Downstream Products

144797-57-9Relevant academic research and scientific papers

SUBSTITUTED NAPHTHYRIDINES AND THEIR USE AS MEDICAMENTS

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Page/Page column 17, (2012/02/06)

The invention relates to new substituted naphthyridines of formula 1, as well as pharmacologically acceptable salts, diastereomers, enantiomers, racemates, hydrates or solvates thereof, wherein R1 is selected from among —O—R3 or —NR3R4,R3 is C1-6-alkyl which is substituted by R5 and R6,R5 is selected from hydrogen, branched or linear C1-6-alkyl, C2-6-alkenyl, —C1-6-alkylen-O—C1-3-alkyl, C1-3-haloalkyl,R6 is ring X wherein n is either 0 or 1, and is a either a single or a double bond andwherein A, B, D and E are each independently from one another selected from CH2, CH, C, N, NH, O or S and wherein ring X is attached to the molecule either via position A, B, D or E, wherein said ring X may optionally be further substituted by one, two or three residues each selected individually from the group consisting of -oxo, hydroxy, —C1-3-alkyl, —C1-3-haloalkyl, —O—C1-3-alkyl, —C1-3-alkanol and halogen,and wherein R4, R2, R7, R8, R9, R10, R11 and Q may have the meanings as given in claim 1, as well as pharmaceutical compositions containing these compounds.

SUBSTITUTED NAPHTHYRIDINES AND THEIR USE AS SYK KINASE INHIBITORS

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Page/Page column 34, (2011/08/21)

The invention relates to new substituted naphthyridines of formula (1), as well as pharmacologically acceptable salts, diastereomers, enantiomers, racemates, hydrates or solvates thereof, wherein R1 is selected from among -O-R3 or -NR3R4, R3 is C1-6-alkyl which is substituted by R5 and R6 R5 is selected from hydrogen, branched or linear C1-6-alkyl, C2-6-alkenyl, -C1-6-alkylen-O-C1-3-alkyl, C1-3-haloalkyl, R6 is ring X wherein n is either 0 or 1, and Formula (I) is a either a single or a double bond and wherein A, B, D and E are each independently from one another selected from CH2, CH, C, N, NH, O or S and wherein ring X is attached to the molecule either via position A, B, D or E, wherein said ring X may optionally be further substituted by one, two or three residues each selected individually from the group consisting of -oxo, hydroxy, -C1-3-alkyl, -C1-3-haloalkyl, -O-C1-3-alkyl, -C1-3-alkanol and halogen, and wherein R4, R2, R7, R8, R9, R10, R11 and Q may have the meanings as given in claim 1, as well as pharmaceutical compositions containing these compounds.

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