1448021-10-0

Basic information

• Product Name: C₂₇H₃₆FN₃O₈S
• CAS NO: 1448021-10-0
• Molecular Weight: 581.663
• Mol File: 1448021-10-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₇H₃₆FN₃O₈S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₇H₃₆FN₃O₈S(1448021-10-0)
• EPA Substance Registry System: C₂₇H₃₆FN₃O₈S(1448021-10-0)

Safety Data

• Hazardous Substances Data: 1448021-10-0(Hazardous Substances Data)

Upstream product

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Relevant articles and documents

Construction of functionalized tricyclic dihydropyrazino-quinazolinedione chemotypes via an Ugi/N-acyliminium ion cyclization cascade

Dihydropyrazino-quinazolinedione chemotypes are complex and structurally challenging structures of biological interest, being found in the marine alkaloids such as brevianamide M-N and fumiquinazolines A-C. Herein we report the synthesis of this tricyclic system in three synthetic operations by means of an Ugi multi-component reaction (MCR) followed by a tandem N-acyliminium ion cyclization-intramolecular nucleophilic addition reaction sequence. Additional structural diversification for further library enrichment was also accomplished via sequential N-alkylation and N-acylation/sulfonation.