1448024-77-8Relevant academic research and scientific papers
One-pot synthesis of 2-aminotetrahydrothiopyrano[4,3-b]-pyran-3- carbonitrile derivatives using mesoporous NH2-MCM-41
Mirza-Aghayan, Maryam,Saravani, Farhad,Tarlani, Ali Akbar,Abaee, Mohammad Saeed,Boukherroub, Rabah
, p. 1699 - 1704 (2013)
A facile and general procedure is presented for the one-pot synthesis of 2-aminotetrahydrothiopyrano[4,3-b]pyran-3-carbonitrile derivatives. It is based on the threecomponent condensation of aliphatic, aromatic, or heterocyclic aldehydes, malononitrile, and thiopyran in the presence of mesoporous amino-functionalized MCM-41 silica in ethanol. This efficient technique has the advantage of giving 2-aminotetrahydrothiopyrano[4,3-b]pyran-3-carbonitrile derivatives using a heterogeneous mesoporous reagent in high yields, in short reaction times, and offers a simple product isolation procedure. Springer-Verlag Wien 2013.
