1448147-55-4

Basic information

• Product Name: 2,3,3-trimethyl-1-[(4-nitrophenyl)methyl]-3H-indol-1-ium-5-sulfonate
• Synonyms: 2,3,3-trimethyl-1-[(4-nitrophenyl)methyl]-3H-indol-1-ium-5-sulfonate
• CAS NO: 1448147-55-4
• Molecular Weight: 374.417
• Mol File: 1448147-55-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,3,3-trimethyl-1-[(4-nitrophenyl)methyl]-3H-indol-1-ium-5-sulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,3-trimethyl-1-[(4-nitrophenyl)methyl]-3H-indol-1-ium-5-sulfonate(1448147-55-4)
• EPA Substance Registry System: 2,3,3-trimethyl-1-[(4-nitrophenyl)methyl]-3H-indol-1-ium-5-sulfonate(1448147-55-4)

Safety Data

• Hazardous Substances Data: 1448147-55-4(Hazardous Substances Data)

Upstream product

• 132557-72-3 2,3,3-trimethylindole-5-sulfonic acid 
• 98-71-5 4-hydrazino-benzenesulfonic acid 
• 563-80-4 3-methyl-butan-2-one 
• 100-11-8 1-bromomethyl-4-nitro-benzene 

Downstream Products

• 1448147-57-6 Cy₅-NBA-NHS 
• 1448147-56-5 Cy₅-NBA-COOH 

Relevant articles and documents

Synthesis and characterization of a novel near-infrared fluorescent probe for living cells imaging

Currently, optical probes with near-infrared (NIR) fluorescence are of great interest in chemical biology. In the present study, we designed and synthesized a novel NIR fluorescent probe, IR789. IR789 has high selectivity and sensitivity for living cells imaging. The stronger excitation and emission characteristics suggested its dominant optical properties over ICG. IR789 also showed a high affinity and inconspicuous cytotoxicity at the cellular level. The results of fluorescent image in living A549 cells (human lung adenocarcinoma epithelial cell line) further demonstrated its potential applications for biomedical diagnosis in biological systems utilization of nanotechnology.

DYE COMPOSITIONS, METHODS OF PREPARATION, CONJUGATES THEREOF, AND METHODS OF USE

Dye compounds of the formula (1) wherein A is a protective agent group that has a characteristic of modifying the singlet-triplet occupancy of the shown cyanine moiety, and M is a reactive crosslinking group or a group that can be converted to a reactive crosslinking group. Methods for synthesizing the dye compounds and applications for their use are also described.