1448154-08-2Relevant academic research and scientific papers
Hydrogen autotransfer and related dehydrogenative coupling reactions using a rhenium(i) pincer catalyst
Piehl, Patrick,Pe?a-López, Miguel,Frey, Anna,Neumann, Helfried,Beller, Matthias
, p. 3265 - 3268 (2017)
A novel rhenium complex bearing a non-innocent PNP pincer ligand was prepared. This novel catalyst is active in hydrogen autotransfer reactions to form new C-C and C-N bonds. More specifically, valuable alkylations of ketones and sulfonamides with primary alcohols are herein presented. In addition, the first examples of rhenium-catalysed synthesis of pyrroles are described by dehydrogenative coupling of diols, amines and ketones.
Manganese-Catalyzed Multicomponent Synthesis of Pyrroles through Acceptorless Dehydrogenation Hydrogen Autotransfer Catalysis: Experiment and Computation
Borghs, Jannik C.,Azofra, Luis Miguel,Biberger, Tobias,Linnenberg, Oliver,Cavallo, Luigi,Rueping, Magnus,El-Sepelgy, Osama
, p. 3083 - 3088 (2019/01/09)
A new base metal catalyzed sustainable multicomponent synthesis of pyrroles from readily available substrates is reported. The developed protocol utilizes an air- and moisture-stable catalyst system and enables the replacement of themutagenic α-haloketones with readily abundant 1,2-diols. Moreover, the presented method is catalytic in base and the sole byproducts of this transformation are water and hydrogen gas. Experimental and computational mechanistic studies indicate that the reaction takes place through a combined acceptorless dehydrogenation hydrogen autotransfer methodology.
Multicomponent reactions in PEG-400: Ruthenium-catalyzed synthesis of substituted pyrroles
Chandrasekhar, Srivari,Patro, Vidyavathi,Chavan, Lahu N.,Chegondi, Rambabu,Grée, René
supporting information, p. 5932 - 5935 (2015/01/08)
An efficient and eco-friendly method for the synthesis of substituted pyrroles has been developed via ruthenium-catalyzed multicomponent reaction of ketone, amine, and ethylene glycol in PEG-400 as solvent medium without using any external ligand. The cat
General and regioselective synthesis of pyrroles via ruthenium-catalyzed multicomponent reactions
Zhang, Min,Fang, Xianjie,Neumann, Helfried,Beller, Matthias
supporting information, p. 11384 - 11388 (2013/08/23)
A general and highly regioselective synthesis of pyrroles via ruthenium-catalyzed three-component reactions has been developed. A variety of ketones including less reactive aryl and alkyl substrates were efficiently converted in combination with different
