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1448186-47-7

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1448186-47-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1448186-47-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,4,8,1,8 and 6 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1448186-47:
(9*1)+(8*4)+(7*4)+(6*8)+(5*1)+(4*8)+(3*6)+(2*4)+(1*7)=187
187 % 10 = 7
So 1448186-47-7 is a valid CAS Registry Number.

1448186-47-7Downstream Products

1448186-47-7Relevant articles and documents

Small-molecule inhibitors of the interaction between the E3 ligase VHL and HIF1α

Buckley, Dennis L.,Gustafson, Jeffrey L.,Van-Molle, Inge,Roth, Anke G.,Tae, Hyun Seop,Gareiss, Peter C.,Jorgensen, William L.,Ciulli, Alessio,Crews, Craig M.

supporting information, p. 11463 - 11467 (2013/01/15)

By design: Novel small-molecule inhibitors of the interaction between the von Hippel-Lindau ligase (VHL) and its molecular target HIF1α, a transcription factor involved in oxygen sensing, have been developed and studied. The most potent inhibitor binds with an IC50 value of 0.9-μM and is thus the first sub-micromolar inhibitor of the VHL-HIF1α interaction. Copyright

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