1448424-56-3Relevant academic research and scientific papers
Synthesis of C-2 arylated tryptophan amino acids and related compounds through palladium-catalyzed C-H Activation
Preciado, Sara,Mendive-Tapia, Lorena,Albericio, Fernando,Lavilla, Rodolfo
, p. 8129 - 8135 (2013/09/12)
Tryptophan (Trp) and tryptophan derivatives are C2-arylated. A C-H activation process allows the preparation of both protected and unprotected arylated-Trp amino acids, directly from the amino acid precursor and aryl iodides. The obtained compounds are suitable for standard solid-phase peptide synthesis.
