1448459-91-3

Upstream product

• 824-94-2 p-methoxybenzyl chloride 
• 1448459-82-2 5-iodo-N,N-bis(4-methoxybenzyl)pyrimidin-2-amine 
• 1448459-86-6 (Z)-methyl 2-acetamido-3-(2-(bis(4-methoxybenzyl)amino)pyrimidin-5-yl)acrylate 

Relevant academic research and scientific papers

Asymmetric synthesis of aminopyrimidine and cyclic guanidine amino acids

Syntheses of amino acids with aminopyrimidine and cyclic guanidine side chains are described. The synthetic route employed Heck coupling of methyl 2-acetamidoacrylate to 4-methoxybenzyl protected 2-amino-5-iodopyrimidine, followed by Rh(I)-catalyzed asymm