144848-62-4

Upstream product

• 144848-60-2 (3aS,3bR,7aS,8aR)-8a-Fluoromethyl-2,2,5,5-tetramethyl-tetrahydro-[1,3]dioxolo[4,5]furo[3,2-d][1,3]dioxine 
• 17682-70-1 2,3:4,6-bis-O-isopropylidene-L-sorbose 
• 144848-59-9 Trifluoro-methanesulfonic acid (3aS,3bR,7aS,8aS)-2,2,5,5-tetramethyl-tetrahydro-[1,3]dioxolo[4,5]furo[3,2-d][1,3]dioxin-8a-ylmethyl ester 
• 144848-61-3 (3aR,5S,6R,6aS)-3a-Fluoromethyl-5-hydroxymethyl-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-ol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 73861-92-4 (3R,4R,5S)-2-Methyl-piperidine-3,4,5-triol 

Relevant academic research and scientific papers

Fluorinated 1,5-Dideoxy-1,5-iminoalditols: Synthesis of 1,5,6-Trideoxy-6-fluoro-1,5-imino-D-glucitol (1,6-Dideoxy-6-fluoronojirimycin) and 1,4,5-Trideoxy-4-fluoro-1,5-imino-D-ribitol (1,2,5-Trideoxy-2-fluoro-1,5-imino-L-ribitol)

An efficient synthesis of 1,5,6-trideoxy-6-fluoro-1,5-imino-D-glucitol 13 from inexpensive L-sorbose by way of reductive amination of 12 is described.Synthesis of 1,4,5-trideoxy-4-fluoro-1,5-imino-D-ribitol (1,2,5-trideoxy-2-fluoro-1,5-imino-L-ribitol) 19