1448531-06-3Relevant academic research and scientific papers
Synthetic studies on lemonomycin: Construction of the tetracyclic core
Jiménez-Somarribas, Alberto,Williams, Robert M.
, p. 7505 - 7512 (2013)
A substrate-induced stereocontrol strategy was used to gain access to the tetracyclic core of (-)-lemonomycin. An advanced intermediate was prepared from a known substituted tyrosinol through a 16-step sequence, which involved a Pictet-Spengler reaction, a [3+2] dipolar cycloaddition and an enamide hydrogenation.
