1448531-87-0

Basic information

• Product Name: 1-(3,5-dimethyl-2-(tosylamino)phenyl)prop-2-yn-1-ol
• Synonyms: 1-(3,5-dimethyl-2-(tosylamino)phenyl)prop-2-yn-1-ol
• CAS NO: 1448531-87-0
• Molecular Weight: 329.42
• Mol File: 1448531-87-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(3,5-dimethyl-2-(tosylamino)phenyl)prop-2-yn-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3,5-dimethyl-2-(tosylamino)phenyl)prop-2-yn-1-ol(1448531-87-0)
• EPA Substance Registry System: 1-(3,5-dimethyl-2-(tosylamino)phenyl)prop-2-yn-1-ol(1448531-87-0)

Safety Data

• Hazardous Substances Data: 1448531-87-0(Hazardous Substances Data)

Upstream product

• 70128-12-0 2-amino-3,5-dimethyl-benzaldehyde 
• 98-59-9 p-toluenesulfonyl chloride 
• 1439384-40-3 C₁₆H₁₇NO₃S 
• 4301-14-8 acetylenemagnesium bromide 
• 14438-32-5 3,5-dimethylanthranilic acid 

Downstream Products

• 1448809-02-6 2-(iodomethylene)-5,7-dimethyl-1-tosylindolin-3-one 
• 1448809-01-5 2-(iodomethylene)-5,7-dimethyl-1-tosylindolin-3-one 
• 1448531-95-0 5,7-dimethyl-1-tosyl-1H-indole-2-carbaldehyde 

Relevant articles and documents

Metal-free synthesis of 1H-indole-2-carbaldehydes by N-iodosuccinimide- mediated cyclization of 1-(2′-anilinyl)prop-2-yn-1-ols in water. A formal synthesis of (R)-calindol

A N-iodosuccinimide (NIS)-mediated method to prepare 1H-indole-2- carbaldehydes efficiently from cycloisomerization of 1-(2-aminophenyl)prop-2-yn- 1-ols is described. The reaction is operationally straightforward and accomplished in good to excellent yiel