1448541-52-3Relevant academic research and scientific papers
Regioselective ring-opening reaction of 2-trifluoromethyl-N-tosylaziridine with some nucleophiles under basic conditions
Takehiro, Yui,Hirotaki, Kensuke,Takeshita, Chihomi,Furuno, Hiroshi,Hanamoto, Takeshi
, p. 7448 - 7454 (2013)
The ring-opening reaction of 2-trifluoromethyl-N-tosylaziridine with a variety of heteroatom- and carbon-centered nucleophiles was achieved under basic conditions in good to high yield with excellent regioselectivity. These findings enabled an easy access to useful α-trifluoromethyl-N- tosylmethylamine derivatives, such as 1,2-aminoalcohol, 1,2-diamine, 1,2-aminothiol, and distant secondary amine.
