1448547-85-0Relevant academic research and scientific papers
Rh(III)-catalyzed halogenation of vinylic C-H bonds: Rapid and general access to Z-halo acrylamides
Kuhl, Nadine,Schroeder, Nils,Glorius, Frank
, p. 3860 - 3863 (2013/09/02)
Herein, the regio- and stereoselective iodination, along with some examples for the bromination, of readily available acrylamides to access a variety of differently substituted Z-haloacrylic acid derivatives is reported. The reaction proceeds under mild conditions via a Rh(III)-catalyzed C-H-activation/ halogenation mechanism and represents a rare example of a direct halogenation of electron-poor acrylic acid derivatives.
Dendralene synthesis: Rhodium(III)-catalyzed alkenyl C-H activation and coupling reaction with allenyl carbinol carbonate
Wang, Honggen,Beiring, Bernhard,Yu, Da-Gang,Collins, Karl D.,Glorius, Frank
, p. 12430 - 12434 (2013/12/04)
[3]DendrAl(l)ene! A new synthesis of [3]dendralenes is based on a Rh III-catalyzed alkenyl C-H activation and coupling reaction with allenyl carbinol carbonates (see scheme; DG=directing group). A variety of [3]dendralenes with diverse substitution patterns are accessible with good efficiency. The reaction is highly stereoselective and compatible with different directing groups and numerous functional groups. Copyright
