1448548-02-4

Basic information

• Product Name: (Z)-3-bromo-N,N-diisopropyl-2-methyl-3-phenylacrylamide
• Synonyms: (Z)-3-bromo-N,N-diisopropyl-2-methyl-3-phenylacrylamide
• CAS NO: 1448548-02-4
• Molecular Weight: 324.261
• Mol File: 1448548-02-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-3-bromo-N,N-diisopropyl-2-methyl-3-phenylacrylamide(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-3-bromo-N,N-diisopropyl-2-methyl-3-phenylacrylamide(1448548-02-4)
• EPA Substance Registry System: (Z)-3-bromo-N,N-diisopropyl-2-methyl-3-phenylacrylamide(1448548-02-4)

Safety Data

• Hazardous Substances Data: 1448548-02-4(Hazardous Substances Data)

Upstream product

• 38449-13-7 2-methyl-3-phenylacryloyl chloride 
• 1199-77-5 α-methylcinnamic acid 

Relevant articles and documents

Rh(III)-catalyzed halogenation of vinylic C-H bonds: Rapid and general access to Z-halo acrylamides

Herein, the regio- and stereoselective iodination, along with some examples for the bromination, of readily available acrylamides to access a variety of differently substituted Z-haloacrylic acid derivatives is reported. The reaction proceeds under mild conditions via a Rh(III)-catalyzed C-H-activation/ halogenation mechanism and represents a rare example of a direct halogenation of electron-poor acrylic acid derivatives.