1448549-62-9Relevant academic research and scientific papers
SELECTIVE ALLOSTERIC MODULATORS OF THE SEROTONIN TRANSPORTER
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, (2013/08/15)
Compounds of formula (I) are provided wherein R1 represents H, CN and CF3; R2 represents 1-naphthyl, 3,5-dichlorophenyl, 4-(4-fluorophenylthio)phenyl or phenyl substituted with one or more substituent selected from halogen, methoxy, cyano, methyl and trifluorom ethyl; R3 and R4 independently represent H, C1-3-alkyl or R3 and R4 together with the carbon atom to which they are attached form a C4-6-cyclic alkyl; R5 and R6 independently represent H or C1-6-alkyl; n represents 1 or 2; and pharmaceutically acceptable acid addition salts thereof, provided that if n is 2 then R2 is not 1-naphthyl, which compounds are selective allosteric SERT ligands.
