1448637-94-2Relevant academic research and scientific papers
Synthesis of azetidines and pyrrolidines via iodocyclisation of homoallyl amines and exploration of activity in a zebrafish embryo assay
Feula, Antonio,Dhillon, Sundeep S.,Byravan, Rama,Sangha, Mandeep,Ebanks, Ronald,Hama Salih, Mariwan A.,Spencer, Neil,Male, Louise,Magyary, Istvan,Deng, Wei-Ping,Müller, Ferenc,Fossey, John S.
supporting information, p. 5083 - 5093 (2013/08/23)
Room temperature iodocyclisation of homoallylamines stereoselectively delivers functionalised 2-(iodomethyl)azetidine derivatives in high yield. Increasing reaction temperature from 20 °C to 50°C switches the reaction outcome to realise the stereoselectiv
