1448687-39-5

Basic information

• Product Name: C₂₂H₃₁N₅O₃S
• CAS NO: 1448687-39-5
• Molecular Weight: 445.586
• Mol File: 1448687-39-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₂H₃₁N₅O₃S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₃₁N₅O₃S(1448687-39-5)
• EPA Substance Registry System: C₂₂H₃₁N₅O₃S(1448687-39-5)

Safety Data

• Hazardous Substances Data: 1448687-39-5(Hazardous Substances Data)

Upstream product

• 1448687-30-6 C₁₇H₂₇N₅O₃ 
• 1448687-28-2 C₁₇H₂₅N₃O₄ 
• 1448687-26-0 C₁₅H₂₇N₃O₂ 
• 144222-22-0 tert-butyl 4-(aminomethyl)piperidine-1-carboxylate 

Relevant articles and documents

Synthesis and the 5-HT6 receptor antagonistic effect of 3-arylsulfonylamino-5,6-dihydro-6-substituted pyrazolo[3,4]pyridinones for neuropathic pain treatment

A novel series of 3-arylsulfonylamino-5,6-dihydro-6-substituted-1H- pyrazolo[3,4-c]pyridine-7-ones was designed and synthesized as 5-HT6 ligands. Among the derivatives synthesized, the lead compound, 12b, having piperidine functionality at the 6-position and (1-naphthyl)sulfonamino at the 3-position of the core structure showed the most potent 5-HT6 inhibitory activity in vitro, good stability without CYP liability, and good neuropathic pain alleviation activity in a rat animal model.