1448692-20-3Relevant academic research and scientific papers
Formal [4+1] annulation of α,α-dialkyl β-oxo amides and dimethylsulfoxonium methylide: A synthetic route to β-hydroxy-γ- lactams
Zhang, Dingyuan,Zhang, Qian,Zhang, Ning,Zhang, Rui,Liang, Yongjiu,Dong, Dewen
, p. 7358 - 7360 (2013/09/23)
A facile and efficient one-pot synthesis of β-hydroxy-γ-lactams from α,α-dialkyl β-oxo amides and trimethylsulfoxonium iodide in the presence of sodium hydride via a tandem Corey-Chaykovsky reaction and an intramolecular lactamization process is developed
