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CAS

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1448724-09-1

UM171 is a compound that has the ability to stimulate the expansion of human cord blood cells ex vivo, which can reconstitute human hematopoiesis in immunocompromised mice. This characteristic makes it a potential candidate for various applications in the field of medicine, particularly in the areas of hematopoietic stem cell transplantation and gene therapy.

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  • N1-[2-benzyl-7-(2-methyl-1,2,3,4-tetrazol-5-yl)-9H-pyrimido[4,5-b]indol-4-yl]cyclohexane-1,4-diamine

    Cas No: 1448724-09-1

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  • 1448724-09-1 Structure

  • Basic information

    1. Product Name: UM171
    2. Synonyms: UM171
    3. CAS NO:1448724-09-1
    4. Molecular Formula: C25H27N9
    5. Molecular Weight: 453.54218
    6. EINECS: -0
    7. Product Categories: N/A
    8. Mol File: 1448724-09-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.49±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 11.25±0.50(Predicted)
    10. CAS DataBase Reference: UM171(CAS DataBase Reference)
    11. NIST Chemistry Reference: UM171(1448724-09-1)
    12. EPA Substance Registry System: UM171(1448724-09-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1448724-09-1(Hazardous Substances Data)

1448724-09-1 Usage

Uses

Used in Hematopoietic Stem Cell Transplantation:
UM171 is used as a stimulant for the expansion of human cord blood cells, which can be beneficial for hematopoietic stem cell transplantation. The compound can potentially enhance the success rate of transplantation procedures by increasing the number of viable stem cells available for transplantation.
Used in Gene Therapy:
UM171 is also used as a potential agent in gene therapy, particularly for conditions that involve hematopoietic stem cells. The compound's ability to stimulate the expansion of these cells can be utilized to improve the effectiveness of gene therapy treatments by providing a larger pool of cells for manipulation and subsequent reintroduction into the patient's body.

Check Digit Verification of cas no

The CAS Registry Mumber 1448724-09-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,4,8,7,2 and 4 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1448724-09:
(9*1)+(8*4)+(7*4)+(6*8)+(5*7)+(4*2)+(3*4)+(2*0)+(1*9)=181
181 % 10 = 1
So 1448724-09-1 is a valid CAS Registry Number.

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