144880-70-6Relevant articles and documents
SOME REACTIONS OF 6-CHLORO-2-METHYL-4H-1-BENZOPYRAN-4-ONE. PART II
Salem, Mounir A. I.,Hamed, Ashraf A.,El-Shekeil, Ali G.,Qui, A. S. Baba,Madkour, Hassan M. F.
, p. 605 - 618 (2007/10/03)
6-Chloro-2-methyl-4H-1-benzopyran-4-one (I) gave the isoxazole derivative IIa on reaction with hydroxylamine hydrochloride. The action of hydrazine and phenylhydrazine on I resulted in pyrazole dervatives IIIa and IIIb, respectively. The reactivity of I with ethyloxalate and aromatic nitroso compounds have been investigated. Phthalide VIIIa derived from the chromone I was synthesised and rearranged easily into phthalone IX upon refluxing with alcoholic sodium methoxide. Cleavage of VIIIa with amines and hydrazine hydrate was studied. Thiation of phthalide VIIIa with either Lawesson's reagent or phosphorous pentasulphide yielded the corresponding thione VIIIe.