144881-21-0

Basic information

• Product Name: 4',9,9'-Trihydroxy-3'-methoxy- 3,7'-epoxy-4,8'-oxyneolignan
• Synonyms: 4',9,9'-Trihydroxy-3'-methoxy- 3,7'-epoxy-4,8'-oxyneolignan;(2S,3S)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-propanol
• CAS NO: 144881-21-0
• Molecular Formula: C₁₉H₂₂O₆
• Molecular Weight: 346.37438
• Mol File: 144881-21-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4',9,9'-Trihydroxy-3'-methoxy- 3,7'-epoxy-4,8'-oxyneolignan(CAS DataBase Reference)
• NIST Chemistry Reference: 4',9,9'-Trihydroxy-3'-methoxy- 3,7'-epoxy-4,8'-oxyneolignan(144881-21-0)
• EPA Substance Registry System: 4',9,9'-Trihydroxy-3'-methoxy- 3,7'-epoxy-4,8'-oxyneolignan(144881-21-0)

Safety Data

• Hazardous Substances Data: 144881-21-0(Hazardous Substances Data)

Usage

Uses

Used in Antioxidant Applications:
4',9,9'-Trihydroxy-3'-methoxy-3,7'-epoxy-4,8'-oxyneolignan is used as an antioxidant agent for its ability to protect against oxidative stress. Its antioxidant properties make it a potential candidate for use in various health and wellness applications, as well as in the development of pharmaceuticals aimed at reducing oxidative damage in the body.
Used in Anti-Inflammatory Applications:
In the field of anti-inflammatory applications, 4',9,9'-Trihydroxy-3'-methoxy-3,7'-epoxy-4,8'-oxyneolignan is used to reduce inflammation. Its anti-inflammatory properties suggest that it could be beneficial in treating conditions characterized by excessive inflammation, such as arthritis or other inflammatory disorders.
Used in Cancer Therapy:
4',9,9'-Trihydroxy-3'-methoxy-3,7'-epoxy-4,8'-oxyneolignan is used as a potential cancer therapy agent due to its ability to inhibit the growth of cancer cells. Its potential role in cancer treatment is currently under investigation, with research exploring its effects on various types of cancer and its potential synergistic effects when combined with conventional cancer therapies.
Used in Neuroprotective Applications:
In the field of neuroprotection, 4',9,9'-Trihydroxy-3'-methoxy-3,7'-epoxy-4,8'-oxyneolignan is used for its potential neuroprotective benefits. Research has shown that this compound may help protect neurons from damage, making it a promising candidate for the development of treatments for neurodegenerative diseases such as Alzheimer's or Parkinson's.
Used in Cardiovascular Applications:
4',9,9'-Trihydroxy-3'-methoxy-3,7'-epoxy-4,8'-oxyneolignan is used in cardiovascular applications for its potential cardiovascular benefits. Its effects on the cardiovascular system are currently being studied, with the aim of developing new treatments for heart disease and other related conditions.

Upstream product

• 21204-67-1 methyl (triphenylphosphoranylidene)acetate 

Relevant articles and documents

New neolignan and phenylpropanoid glycosides in Juniperus communis var. depressa

Two new neolignan glucosides (junipercomnosides C and D) and two new phenypropanoid glycosides (junipercomnosides E and F) were isolated from aerial parts of Juniperus communia var. depressa along with seven known phenylpropanoid glycosides. The structures of the isolated compounds were determined by spectral analysis, in particular by the detailed analysis of 2D NMR and CD spectra.

First asymmetric synthesis of chiral 1,4-benzodioxane lignans

An asymmetric and regioselective total synthesis approach to 1,4-benzodioxane lignans was reported in which (2R,3R)- and (2S,3S)-3-(4-hydroxy-3-methoxyphenyl)-2-hydroxymethyl-1,4-benzodi oxan-6-carbaldehyde were synthesized firstly. A natural 1,4-benzodioxane neolignan was synthesized firstly by the synthesis approach. (C) 2000 Elsevier Science Ltd.