1448819-46-2Relevant academic research and scientific papers
Electrochemical Oxidative Aryl(alkyl)trifluoromethylation of Allyl Alcohols via 1,2-Migration
Guan, Zhipeng,Wang, Huamin,Huang, Yange,Wang, Yunkun,Wang, Shengchun,Lei, Aiwen
supporting information, p. 4619 - 4622 (2019/06/17)
An electrochemical oxidative difunctionalization of allyl alcohols for the synthesis of β-trifluoromethyl ketones is achieved through a 1,2-migration process. A series of β-trifluoromethyl ketones can be facilely obtained utilizing CF3SO2
Carbotrifluoromethylation of Allylic Alcohols via 1,2-Aryl Migration Promoted by Visible-Light-Induced Photoredox Catalysis
Cai, Shunyou,Tian, Yu,Zhang, Jinwang,Liu, Zhiji,Lu, Maojian,Weng, Wen,Huang, Mingqiang
, p. 4084 - 4088 (2018/10/02)
Visible-light-enabled photocatalytic carbotrifluoro-methylations of allylic alcohols and sodium triflinate were explored through 1,2-migration of an aryl group, affording an efficient method for synthesis of β-trifluoromethyl-α-substituted carbonyl compou
Iron-catalyzed trifluoromethylation with concomitant C-C bond formation via 1,2-migration of an aryl group
Egami, Hiromichi,Shimizu, Ryo,Usui, Yoshihiko,Sodeoka, Mikiko
supporting information, p. 7346 - 7348 (2013/09/23)
Iron-catalyzed trifluoromethylation with concomitant 1,2-migration of an aryl group starting from diaryl allyl alcohol was achieved under mild conditions. This reaction system affords α-substituted-β- trifluoromethyl carbonyl compounds in high efficiency.
Copper-catalyzed trifluoromethylation-initiated radical 1,2-aryl migration in α,α-diaryl allylic alcohols
Liu, Xiaowu,Xiong, Fei,Huang, Xuanping,Xu, Liang,Li, Pengfei,Wu, Xiaoxing
supporting information, p. 6962 - 6966 (2013/07/26)
Not only symmetrical, but also unsymmetrical α,α-diaryl allylic alcohols are employed as substrates in the title reaction. A number of arenes and even heteroarenes underwent radical 1,2-aryl migration ("neophyl rearrangement") to produce α-aryl β-trifluoromethyl ketones. The preferential migration of electron-deficient aryl groups over electron-rich ones in unsymmetrical substrates supports the radical mechanism, which was further confirmed by DFT calculations. Copyright
