1448819-83-7Relevant academic research and scientific papers
Facile preparation of 2-aryl-3-iodopyrroles with N-tosyl 4-aryl-3-butyn-1-ylamines, I2, andtBuOK
Naruto, Hiroki,Shibasaki, Kaho,Togo, Hideo
, p. 1091 - 1118 (2021/06/21)
Treatment of N-tosyl 4-aryl-3-butyn-1-ylamines with I2 and K2CO3, followed by the reaction withtBuOK under mild conditions gave 2-aryl-3-iodopyrroles in good yields. The present approach is a one-pot method for the preparation of 2-aryl-3-iodopyrroles from N-tosyl 4-aryl-3-butyn-1-ylamines, which could be easily prepared from aryl iodides, N-(3-butyn-1-yl)phthalimides, and p-toluenesulfonyl chloride.
Selective ruthenium-catalyzed three-component synthesis of pyrroles
Zhang, Min,Neumann, Helfried,Beller, Matthias
supporting information, p. 597 - 601 (2013/02/23)
It's a snap: A novel catalytic three-component coupling reaction using simple and easily available substrates leads to a wide range of substituted pyrroles with high regioselectively (see scheme; Xantphos=9,9-dimethyl-4,5- bis(diphenylphosphino)xanthene). Copyright
