144882-80-4

Basic information

• Product Name: (E)-5-chloro-5-(phenylsulfinyl)-2-tetradecen-4-one
• CAS NO: 144882-80-4
• Molecular Weight: 368.968
• Mol File: 144882-80-4.mol

Chemical Properties

• CAS DataBase Reference: (E)-5-chloro-5-(phenylsulfinyl)-2-tetradecen-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-5-chloro-5-(phenylsulfinyl)-2-tetradecen-4-one(144882-80-4)
• EPA Substance Registry System: (E)-5-chloro-5-(phenylsulfinyl)-2-tetradecen-4-one(144882-80-4)

Safety Data

• Hazardous Substances Data: 144882-80-4(Hazardous Substances Data)

Upstream product

• 70872-73-0 (1-chloro-decane-1-sulfinyl)-benzene 

Relevant articles and documents

1-Haloalkyl Aryl Sulfoxides as Useful Agents in Synthesis of α-Halo Ketones: A New Synthesis of α-Halo Ketones, α-Halo α,β-Unsaturated Ketones, and α-Halo Cross Dienones from Aldehydes

α-Halo α-sulfinyl ketones were synthesized in two steps from 1-haloalkyl aryl sulfoxides and aldehydes in high yields.Desulfinylation of the α-halo α-sulfinyl ketones was performed with ethylmagnesium bromide in ether at low temperature to afford α-halo ketones via magnesium enolates in high yields.The magnesium enolate intermediates were trapped with various electrophiles such as deuterium oxide, ethyl chloroformate, and chlorotrimethylsilane.Trapping of the magnesium enolate intermediate with carbonyl compounds afforded a new type of the directed aldol reaction.Desulfi nylation of the sulfinyl group of the α-halo α-sulfinyl ketones under thermal conditions gave α-halo α,β-unsatureted ketones or α-halo cross dienones.