1448874-97-2

Upstream product

• 1227268-70-3 methyl 2-oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-6-carboxylate 
• 108-24-7 acetic anhydride 
• 1663-61-2 triethoxymethylbenzene 

Downstream Products

• 1448874-96-1 (Z)-methyl 3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-6-carboxylate 
• 1448875-02-2 (Z)-methyl 3-(((4-((2-(ethyl(methyl)amino)-2-oxoethyl)(methyl)amino)phenyl)amino)(phenyl)methylene)-2-oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-6-carboxylate 

Relevant academic research and scientific papers

METHODS FOR TREATING INFLAMMATORY BOWEL DISEASE

The present disclosure provides methods for treating inflammatory bowel disease including Crohn's disease and ulcerative colitis by administering a compound of Formula (I) and pharmaceutically acceptable derivatives thereof, as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof.

METHODS AND USES OF COMPOUNDS FOR TREATING DISEASE

The present invention provides methods for treating polycystic kidney disease by administering a compound or pharmaceutical composition thereof having the general structural formula (I) and pharmaceutically acceptable derivatives thereof, as described generally and in classes and subclasses herein.

ANTIFIBROTIC COMPOUNDS AND USES THEREOF

The present invention provides compounds having the general structural formula (I), and pharmaceutically acceptable derivatives thereof, as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases involving abnormal or excessive fibrosis.