Cas 1448898-22-3,methyl 6-(4-bromophenyl)-8-(methylthio)-2-phenyl-4,5-dihydro-2H-benzo[e]indazole-9-carboxylate

1448898-22-3

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Basic information

Product Name: methyl 6-(4-bromophenyl)-8-(methylthio)-2-phenyl-4,5-dihydro-2H-benzo[e]indazole-9-carboxylate
Synonyms: methyl 6-(4-bromophenyl)-8-(methylthio)-2-phenyl-4,5-dihydro-2H-benzo[e]indazole-9-carboxylate
CAS NO:1448898-22-3
Molecular Formula:
Molecular Weight: 505.435
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: methyl 6-(4-bromophenyl)-8-(methylthio)-2-phenyl-4,5-dihydro-2H-benzo[e]indazole-9-carboxylate(CAS DataBase Reference)
NIST Chemistry Reference: methyl 6-(4-bromophenyl)-8-(methylthio)-2-phenyl-4,5-dihydro-2H-benzo[e]indazole-9-carboxylate(1448898-22-3)
EPA Substance Registry System: methyl 6-(4-bromophenyl)-8-(methylthio)-2-phenyl-4,5-dihydro-2H-benzo[e]indazole-9-carboxylate(1448898-22-3)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1448898-22-3(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1448898-22-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,4,8,8,9 and 8 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1448898-22:
(9*1)+(8*4)+(7*4)+(6*8)+(5*8)+(4*9)+(3*8)+(2*2)+(1*2)=223
223 % 10 = 3
So 1448898-22-3 is a valid CAS Registry Number.

1448898-22-3Upstream product

1448898-22-3Downstream Products

1448898-33-6 methyl 8-(methylsulfonyl)-2-phenyl-6-(p-tolyl)-4,5-dihydro-2H-benzo[e]indazole-9-carboxylate

1448898-22-3Relevant academic research and scientific papers

Synthesis of substituted 2H-benzo[e]indazole-9-carboxylate as a potent antihyperglycemic agent that may act through IRS-1, Akt and GSK-3β pathways

Taneja, Gaurav,Gupta, Chandra Prakash,Mishra, Shachi,Srivastava, Rohit,Rahuja, Neha,Rawat, Arun Kumar,Pandey, Jyotsana,Gupta, Anand P.,Jaiswal, Natasha,Gayen, Jiaur R.,Tamrakar, Akhilesh K.,Srivastava, Arvind Kumar,Goel, Atul

, p. 329 - 337 (2017/03/08)

Based on high throughput screening of our chemical library, we identified two 4,5-dihydro-2H-benzo[e]indazole derivatives (5d and 5g), which displayed a significant effect on glucose uptake in L6 skeletal muscle cells. Based on these lead molecules, a ser

Substituted 4,5-Dihydro-2H-Benzo[e]Indazole-9-Carboxylates For The Treatment Of Diabetes And Related Disorders

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Paragraph 0055; 0056, (2015/02/05)

The present invention relates to the development of novel substituted 4,5-dihydro-2H-benzo[e]indazole-9-carboxylates, which can be used as therapeutic agents for the treatment and prevention of metabolic disorders, and a process of preparing said novel compounds. More particularly, the present invention relates to substituted 4,5-dihydro-2H-benzo[e]indazole-9-carboxylates and their related compounds, processes for preparing the said compounds and to their use in the treatment of diabetes and related metabolic disorders.

SUBSTITUTED 4,5-DIHYDRO-2H-BENZO[E]INDAZOLE-9-CARBOXYLATES FOR THE TREATMENT OF DIABETES AND RELATED DISORDERS

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Page/Page column 8-9, (2013/08/15)

The present invention relates to the development of novel substituted 4,5-dihydro-2H- benzo[e]indazole-9-carboxylates, which can be used as therapeutic agents for the treatment and prevention of metabolic disorders, and a process of preparing said novel compounds. More particularly, the present invention relates to substituted 4,5-dihydro- 2H-benzo[e]indazole-9-carboxylates and their related compounds, processes for preparing the said compounds and to their use in the treatment of diabetes and related metabolic disorders.

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