144890-05-1

Basic information

• Product Name: 3-methyl-4-phenylsulfonyl-2-cycloxexen-1-one
• CAS NO: 144890-05-1
• Molecular Weight: 250.318
• Mol File: 144890-05-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-methyl-4-phenylsulfonyl-2-cycloxexen-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methyl-4-phenylsulfonyl-2-cycloxexen-1-one(144890-05-1)
• EPA Substance Registry System: 3-methyl-4-phenylsulfonyl-2-cycloxexen-1-one(144890-05-1)

Safety Data

• Hazardous Substances Data: 144890-05-1(Hazardous Substances Data)

Upstream product

• 67257-30-1 diethyl 2-oxo-3-butenylphosphonate 
• 5000-44-2 1-phenylsulfonyl-2-propanone 

Relevant articles and documents

A New Annulation Reagent, 2-Oxo-3-alkenylphosphonates. Reactions with Carbonyl-Stabilized Carboanions or Silyl Enol Ethers Leading to Cyclohexanones

The reactions of 2-oxo-3-alkenylphosphonates with carbonyl-stabilized carbanions directly lead to 2-cyclohexen-1-ones through a sequence of Michael reaction and intramolecular Horner-Emmons olefination.On the other hand, the Lewis acid-mediated reactions with silyl enol ethers produce 1,5-diketones as Michael adducts, which then undergo cyclization on treatment with sodium hydride or triethylamine/zinc (II) bromide to afford 2-cyclohexen-1-ones or 2-phosphinyl-2-cyclohexen-1-ones, respectively.