1449005-14-4Relevant academic research and scientific papers
Exploration of imidazole and imidazopyridine dimers as anticancer agents: Design, synthesis, and structure–activity relationship study
Meenakshisundaram, Sangeetha,Manickam, Manoj,Pillaiyar, Thanigaimalai
, (2019)
Dimerization of proteins/receptors plays a critical role in various cellular processes, including cell proliferation and differentiation. Therefore, targeting such dimeric proteins/receptors by dimeric small molecules could be a potential therapeutic appr
Stereochemistry of phosphite addition to azomethine bond of achiral 2,6-pyridinedicarbaldimines and isophthalaldimines - A comparative study
Lewkowski, Jaroslaw,Dziegielewski, Marek
, p. 995 - 1006 (2013/09/02)
The addition of dialkyl H-phosphonates to isophthalaldimines 1a-d and pyridine-2,6-dicarboxaldimines 2a-d was investigated and led to the corresponding aminophosphonates. Diastereoselectivity of the addition to pyridine-2,6-dicarboxaldimines was lower tha
Synthesis of bistetrahydroquinolines as potential anticholinesterasic agents by double diels-alder reactions
Duarte, Yorley,Gutierrez, Margarita,Astudillo, Luis,Alzate-Morales, Jans,Valdes, Natalia
, p. 12951 - 12965 (2013/11/06)
The tetrahydroquinoline ring system is a unit found in many biologically active natural products and pharmacologically relevant therapeutic agents. A new series of bistetrahydroquinolines (bis-THQs) was synthesized using imino Diels-Alder reactions betwee
