1449039-26-2Relevant academic research and scientific papers
Enantioselective Decarboxylative Alkylation of β-Keto Acids to ortho-Quinone Methides as Reactive Intermediates: Asymmetric Synthesis of 2,4-Diaryl-1-benzopyrans
Jeong, Hyun Jung,Kim, Dae Young
, p. 2944 - 2947 (2018)
A novel and efficient asymmetric synthesis of 2,4-diaryl-1-benzopyrans via enantioselective decarboxylative alkylation of β-keto acids to o-QM intermediates, followed by sequential cyclization and dehydration, has been developed. The synthetically useful chiral 2,4-diaryl-1-benzopyran derivatives were obtained in moderate to high yields and high enantioselectivities through a one-pot, two-step sequence. This approach offers a facile way to prepare chiral 2,4-diaryl-1-benzopyran derivatives with a wide range of functional group tolerance.
Shedding light on organocatalysis - Light-assisted asymmetric ion-pair catalysis for the enantioselective hydrogenation of pyrylium ions
Hsiao, Chien-Chi,Liao, Hsuan-Hung,Sugiono, Erli,Atodiresei, Iuliana,Rueping, Magnus
supporting information, p. 9775 - 9779 (2013/08/23)
A new light-driven asymmetric ion-pair catalysis procedure for the metal-free enantioselective hydrogenation of in situ generated pyrylium ions from readily available chalcones was developed (see scheme). The photo-assisted Bronsted acid catalyzed procedure has broad scope and allows, for the first time, access to valuable 4H-chromenes in good yields and with excellent enantioselectivities. Copyright
