14491-68-0Relevant academic research and scientific papers
'Clicking' molecular hooks on silica nanoparticles to immobilize catalytically important metal complexes: The case of gold catalyst immobilization
Ganai, Anal Kr.,Bhardwaj, Rima,Hotha, Srinivas,Gupta, Sayam Sen,Prasad
, p. 2662 - 2670 (2010)
Gold mediated reactions have emerged as one of the best choices for affecting a variety of chemical transformations with a wide range of functional group tolerance. Application of such transformations to industrial processes necessitates immobilization of the Au ions into a matrix for easy separation of the catalyst after reaction. We report the synthesis and characterization of silica nanoparticles in which Au(iii) has been immobilized through a 1,2,3-triazole linkage using an alkynalated picolinic acid exploiting "click chemistry". The Au(iii) immobilized silica nanoparticle has been thoroughly characterized using FT-IR, 13C CP MAS NMR and XPS. The utility of these particles as an easily separable catalyst for the Hashmi phenol synthesis is also reported.
Palladium-catalyzed cleavage of O/N-propargyl protecting groups in aqueous media under a copper-free condition
Pal, Manojit,Parasuraman, Karuppasamy,Yeleswarapu, Koteswar Rao
, p. 349 - 352 (2007/10/03)
(Figure presented) A copper-free palladium-mediated cleavage of O/N-propargyl bonds in aqueous media has been investigated, affording a mild and convenient method for the deprotection of phenols and anilines. The methodology could be utilized for the selective removal of propargyl groups from aryl ethers and amines without affecting a variety of unprotected functional groups present in the substrates. The mechanism and scope of the reaction is discussed.
