1449144-55-1

Basic information

• Product Name: (4-chloro-3-(4-Methylpiperidine-1-carbonyl)phenyl)boronic acid
• Synonyms: (4-chloro-3-(4-Methylpiperidine-1-carbonyl)phenyl)boronic acid
• CAS NO: 1449144-55-1
• Molecular Formula: C13H17BClNO3
• Molecular Weight: 281.54298
• Mol File: 1449144-55-1.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 497.2±55.0 °C(Predicted)
• Appearance: /
• Density: 1.29±0.1 g/cm3(Predicted)
• PKA: 7.89±0.10(Predicted)
• CAS DataBase Reference: (4-chloro-3-(4-Methylpiperidine-1-carbonyl)phenyl)boronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (4-chloro-3-(4-Methylpiperidine-1-carbonyl)phenyl)boronic acid(1449144-55-1)
• EPA Substance Registry System: (4-chloro-3-(4-Methylpiperidine-1-carbonyl)phenyl)boronic acid(1449144-55-1)

Safety Data

• Hazardous Substances Data: 1449144-55-1(Hazardous Substances Data)

Usage

Description

(4-chloro-3-(4-Methylpiperidine-1-carbonyl)phenyl)boronic acid is a chemical compound that features a boronic acid functional group attached to a phenyl ring with a chloro substituent and a 4-methylpiperidine-1-carbonyl group. (4-chloro-3-(4-Methylpiperidine-1-carbonyl)phenyl)boronic acid is known for its ability to form reversible covalent bonds with diols and other Lewis bases, which makes it versatile in various chemical reactions such as Suzuki-Miyaura cross-coupling reactions and as a catalyst in asymmetric transformations. The presence of the 4-methylpiperidine-1-carbonyl group indicates potential applications in medicinal chemistry, as piperidine derivatives are prevalent in pharmaceuticals and exhibit biological activities as neurotransmitter modulators, analgesics, and antipsychotics. The chloro substituent on the phenyl ring may also provide unique properties to the compound, such as modified reactivity or binding affinity.

Uses

Used in Chemical Synthesis:
(4-chloro-3-(4-Methylpiperidine-1-carbonyl)phenyl)boronic acid is used as a synthetic building block for the creation of various complex organic molecules. Its ability to form reversible covalent bonds with diols and other Lewis bases makes it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (4-chloro-3-(4-Methylpiperidine-1-carbonyl)phenyl)boronic acid is used as a key intermediate in the development of new drugs. (4-chloro-3-(4-Methylpiperidine-1-carbonyl)phenyl)boronic acid's structural features, including the 4-methylpiperidine-1-carbonyl group and the chloro substituent on the phenyl ring, may contribute to its potential as a modulator of neurotransmitters, an analgesic, or an antipsychotic agent.
Used in Catalyst Design:
(4-chloro-3-(4-Methylpiperidine-1-carbonyl)phenyl)boronic acid is used as a catalyst in asymmetric transformations, where it can help control the stereochemistry of a reaction, leading to the formation of enantiomerically pure products. This is particularly important in the synthesis of chiral drugs, where the desired biological activity is often associated with a specific enantiomer.
Used in Material Science:
In the field of material science, (4-chloro-3-(4-Methylpiperidine-1-carbonyl)phenyl)boronic acid may be utilized in the development of new materials with unique properties, such as altered reactivity or binding affinity, due to the presence of the chloro substituent on the phenyl ring. These materials could have applications in various industries, including electronics, coatings, and adhesives.