1449215-36-4

Basic information

• Product Name: ethyl 2-(ethyl(4-methoxyphenyl)amino)-2-(thiophen-2-carbonyl)-4-(triethylsilyl)but-3-ynoate
• Synonyms: ethyl 2-(ethyl(4-methoxyphenyl)amino)-2-(thiophen-2-carbonyl)-4-(triethylsilyl)but-3-ynoate
• CAS NO: 1449215-36-4
• Molecular Weight: 485.72
• Mol File: 1449215-36-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 2-(ethyl(4-methoxyphenyl)amino)-2-(thiophen-2-carbonyl)-4-(triethylsilyl)but-3-ynoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-(ethyl(4-methoxyphenyl)amino)-2-(thiophen-2-carbonyl)-4-(triethylsilyl)but-3-ynoate(1449215-36-4)
• EPA Substance Registry System: ethyl 2-(ethyl(4-methoxyphenyl)amino)-2-(thiophen-2-carbonyl)-4-(triethylsilyl)but-3-ynoate(1449215-36-4)

Safety Data

• Hazardous Substances Data: 1449215-36-4(Hazardous Substances Data)

Upstream product

• 1448664-68-3 ethyl 2-oxo-4-(triethylsilyl)but-3-ynoate 
• 1777-03-3 2-triethylsilylacetylene 
• 5271-67-0 2-Thiophenecarbonyl chloride 
• 1449215-20-6 ethyl 2-((4-methoxyphenyl)imino)-4-(triethylsilyl)but-3-ynoate 
• 925-90-6 ethylmagnesium bromide 

Relevant articles and documents

Regioselective tandem N-alkylation/ C-acylation of β,γ-alkynyl α-imino esters

A new synthesis of α-quaternary alkynyl amino esters and allenoates was developed utilizing umpolung N-addition to β,γ-alkynyl α-imino esters followed by regioselective acylation. The reaction exhibits broad substrate generality and unique regioselectivity. Moreover, synthesis of α-quaternary alkynyl amino esters was also carried out via oxidation of the intermediary enolate followed by alkylation.