1449219-71-9Relevant academic research and scientific papers
Aza-michael access to fluoroalkylidene analogues of biomolecules
Prunier, Anais,Calata, Charlene,Legros, Julien,Maddaluno, Jacques,Pfund, Emmanuel,Lequeux, Thierry
, p. 8083 - 8097 (2013)
The synthesis of fluoroaminosulfones derived from piperidine and nucleic bases followed by the study of their chemical behavior in the modified Julia reaction are described. The resulting aminosulfones open a straightforward access to a series of new fluorinated biomolecules including a potent DPP-II inhibitor and acyclonucleoside analogues as potential enzyme inhibitors.
