1449219-72-0Relevant academic research and scientific papers
Aza-michael access to fluoroalkylidene analogues of biomolecules
Prunier, Anais,Calata, Charlene,Legros, Julien,Maddaluno, Jacques,Pfund, Emmanuel,Lequeux, Thierry
, p. 8083 - 8097 (2013/09/12)
The synthesis of fluoroaminosulfones derived from piperidine and nucleic bases followed by the study of their chemical behavior in the modified Julia reaction are described. The resulting aminosulfones open a straightforward access to a series of new fluorinated biomolecules including a potent DPP-II inhibitor and acyclonucleoside analogues as potential enzyme inhibitors.
