1449240-68-9 Usage
Uses
K145 hydrochloride has been used in the analysis of apoptosis.
General Description
K145 hydrochloride (3-(2-Amino-ethyl)-5-[3-(4-butoxyl-phenyl)-propylidene]-thiazolidine-2,4-dione) is an analog of sphingosine.
Biochem/physiol Actions
It has the ability to prevent leukemia cell growth in vitro.
Check Digit Verification of cas no
The CAS Registry Mumber 1449240-68-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,4,9,2,4 and 0 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1449240-68:
(9*1)+(8*4)+(7*4)+(6*9)+(5*2)+(4*4)+(3*0)+(2*6)+(1*8)=169
169 % 10 = 9
So 1449240-68-9 is a valid CAS Registry Number.
1449240-68-9Relevant articles and documents
3-(2-AMINO-ETHYL)-ALKYLIDENE)-THIAZOLIDINE-2,4-DIONE AND 1-(2-AMINO-ETHYL)-ALKYLIDENE-1,3-DIHYDRO-INDOL-2-ONE DERIVATIVES AS SELECTIVE SPHINGOSINE KINASE 2 INHIBITORS
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Page/Page column 27, (2013/08/28)
3-(2-amino-ethyl)-5-[3-(4-substituted-phenyl)-alkylidene)-thiazolidine-2,4-dione and l-(2-amino-ethyl)-3-alkylidene-l,3-dihydro-indol-2-one and derivatives thereof are provided for use as selective SphK2 inhibitors and for use in the treatment of human diseases, such as cancer.
