1449289-64-8

Basic information

• Product Name: C₁₁H₁₂F₃NO₂*C₁₄H₁₉NO₃
• Synonyms: C₁₁H₁₂F₃NO₂*C₁₄H₁₉NO₃
• CAS NO: 1449289-64-8
• Molecular Weight: 496.527
• Mol File: 1449289-64-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₁H₁₂F₃NO₂*C₁₄H₁₉NO₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₁H₁₂F₃NO₂*C₁₄H₁₉NO₃(1449289-64-8)
• EPA Substance Registry System: C₁₁H₁₂F₃NO₂*C₁₄H₁₉NO₃(1449289-64-8)

Safety Data

• Hazardous Substances Data: 1449289-64-8(Hazardous Substances Data)

Upstream product

• 1253055-92-3 methyl 3-amino-4-(2,4,5-trifluorophenyl)butanoate 
• 16859-51-1 (S)-2-pentanamido-3-phenylpropanoic acid 

Downstream Products

• 881995-69-3 (R)-3-amino-4-(2,4,5-trifluorophenyl)butyric acid methyl ester 

Relevant articles and documents

A NOVEL PROCESS FOR THE PREPARATION OF SITAGLIPTIN

The present invention is directed to a process for the preparation of enantiomerically enriched β-amino acid derivatives which are important chiral building blocks and intermediates in pharmaceuticals. More specifically, the invention pertains to a novel process for practically convenient and economically producing enantiomerically enriched β-amino acid derivatives which are useful for the synthesis of amide inhibitors of dipeptidyl peptidase IV like Sitagliptin, which have been used to treat type 2 diabetes.