144935-50-2

Upstream product

• 120-43-4 4-ethoxycarbonylpiperazine 
• 144935-30-8 9-Chloro-2-(3-chloro-propyl)-5-phenyl-4,5-dihydro-2H-6-thia-2,3,10b-triaza-benzo[e]azulen-1-one 
• 144935-09-1 N'-(7-Chloro-2-phenyl-2,3-dihydro-benzo[b][1,4]thiazepin-4-yl)-hydrazinecarboxylic acid ethyl ester 
• 144935-18-2 9-Chloro-5-phenyl-4,5-dihydro-2H-6-thia-2,3,10b-triaza-benzo[e]azulen-1-one 
• 144934-97-4 7-chloro-2,3-dihydro-2-phenyl-1,5-benzothiazepin-4(5H)-thione 
• 144935-01-3 4-methylthio-7-chloro-2,3-dihydro-2-phenyl-1,5-benzothiazepine 

Relevant academic research and scientific papers

Studies on annelated [1,4]benzothiazines and [1,5]benzothiazepines, V: Synthesis and biological activity of N-2 alkylamino derivatives of 4,5-dihydro-s-triazolo[3,4-d]-1,5-benzothiazepine

The synthesis of a new series of N-2 alkylamino derivatives of 4,5-dihydro-s-triazolo[3,4-d]-1,5-benzothiazepine has been accomplished starting from 2,3-dihydro-1,5-benzothiazepin-4(5H)ones and their 2-methyl and 2-aryl derivatives. - All the compounds were tested in vitro for their antimicrobial activity, but none of them showed remarkable activity. - The tricyclic compounds 7a-j, 8a-j, 9a-j, 10a-j, and 11a-j were also screened for their CNS activity in mice and several of them showed interesting activity.