1449411-42-0

Basic information

• Product Name: (3R,4R)-1-benzyl-4-(4-bromophenyl)-2-oxopiperidine-3-carbonitrile
• CAS NO: 1449411-42-0
• Molecular Weight: 369.261
• Mol File: 1449411-42-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3R,4R)-1-benzyl-4-(4-bromophenyl)-2-oxopiperidine-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4R)-1-benzyl-4-(4-bromophenyl)-2-oxopiperidine-3-carbonitrile(1449411-42-0)
• EPA Substance Registry System: (3R,4R)-1-benzyl-4-(4-bromophenyl)-2-oxopiperidine-3-carbonitrile(1449411-42-0)

Safety Data

• Hazardous Substances Data: 1449411-42-0(Hazardous Substances Data)

Upstream product

• 345368-66-3 C₁₇H₁₃BrN₂O 

Relevant articles and documents

One-pot synthesis of optically enriched 2-piperidinones from aliphatic aldehydes and cyanoacrylamides

A highly stereoselective one-pot reaction of aliphatic aldehydes and cyanoacrylamides has been developed. The one-pot reaction includes an organocatalytic Michael addition followed by an intramolecular hemiaminalization. After reduction, optically enriched 2-piperidinones with three contiguous chiral centers were obtained in up to 95% yield and 9:1 dr with 99% ee.